Pings
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8 Answers 5 Votes
How should exposure durations be scaled from studies in mice and rats to humans?
Time-Scaling for Developmental Toxicity Endpoints How should exposure durations be scaled from studies in mice and rats to humans? Is a 10-day rodent exposure equivalent to a 10-day human exposure during gestation?
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28 Answers 54 Votes
For respiratory viruses, should folks wear masks in public a) always, b) if they are or may be infected, or c) if they are afraid of getting infected? Are masks a) protection, or b) social signals?
Since 2020, the public has thought of masks as having a protective purpose, and many rebel at the inconvenience, rationalizing that “they do a poor job of protecting.” Is the current epidemic a good opportunity for government and medicine to teach the folks about the more important virtues of using masks to convey information?
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14 Answers 3 Votes
Any herbal medicines used for hepatitis, possible mechanism of action, and if possible attached pictures of plants with citations
Any herbal medicines used for hepatitis, possible mechanism of action, and if possible attached pictures of plants with citations
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4 Answers 1 Vote
Why is the ammonia/ammonium concentration highly increased during storage of human urine?
Hydrolysis of urine Why is the ammonia/ammonium concentration highly increased during storage of human urine?
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2 Answers 0 Votes
How can scientists reliably detect and mitigate hallucinations in large language models used for scientific writing and literature review?
Large language models are increasingly being utilized for literature reviews, manuscript drafting, and scientific question answering. Hallucinated citations, unsupported assertions and factual errors remain major problems, however. What evaluation methods, benchmarks, human-in-the-loop strategies, or retrieval-augmented strategies have experts found to be most effective in improving factual reliability while maintaining efficiency in scientific research workflows?
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3 Answers 0 Votes
What validated tools or frameworks exist for detecting and mitigating AI/LLM hallucinations in systematic review methodology in resource constrained settings ?
I have published survey based research on AI hallucination awareness among early career medical researchers in Pakistan (medRxiv preprint live). I am seeking expert input on validated detection frameworks or mitigation strategies specifically applicable to systematic review workflows in low and middle income country research contexts where verification infrastructure is limited.
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Answer Accepted 1 Answer 0 Votes
what specific molecular pathways or immune cell subsets should researchers prioritize using flow cytometry to provide clinicians with a truly actionable, targeted immune signature of the patient?
it is a specific question that can help thousands for clinicians and lab experts to find targeted biomarkers that can achieve to diagnose and see a result for their therapies by blocking molecular pathways that can find the biochemical, environmental tumor microenvironment, multiplication, resistance of the tumor and many others and will help to block all mechanisms of the carcinogenesis
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8 Answers 2 Votes
What is the most important part of a scientific article? Let's approach this seriously! Part 2
I have read all the responses to my question, and I find that, except for one, they are largely absurd. There is talk of methodology and results, but as the famous saying goes, “There are lies, big lies, and statistics.” Many articles submitted for publication manipulate data that is either highly misleading or not original at all. I’m unsure if this will be approved on Scipion. What is the most important part of a scientific article? Let’s approach this seriously! I am not at all surprised...
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28 Answers 3 Votes
What are the benefits of strong collaborations between academia and the industry?
It is said that lack of relevant relationships between the industry and academia impede industrial innovations, as a strong bond between both can revolutionise global economy. What is your take on this and what benefits can such relationship between both parties bring?
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12 Answers 0 Votes
The motivation behind conducting a risk assessment
Hello, I understand the purpose of a chemical risk assessment (e.g., setting safe exposure limits). However, I am wondering, in practical terms, what (aside from regulations) causes agencies to conduct these assessments. Consumer concerns? Potential litigation? Political pressure? In other words, what signals do the EPA and other regulatory agencies get that convinces them to conduct an assessment? Thank you.
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