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18 Answers 22 Votes
Could salary be used as a surrogate for smoking when sample data are lacking?
In epidemiology cohort studies, information on smoking status is often times lacking for the study sample, which makes it challenging to characterize the effects of other risk factors on endpoints that are causally related to smoking (e.g., lung cancer mortality). Given the strong inverse reported for smoking and income, could salary be used as a surrogate for smoking when direct data are lacking? or would potential relationships between salary other risk factors (e.g., health care access)...
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2 Answers 1 Vote
How might AI-assisted peer review tools reshape scientific publishing, and what safeguards should be implemented to maintain review quality while addressing the increasing volume of submissions?
The peer-reviewing process is being faced with ever-growing challenges as submission rates are still rising exponentially in all areas. Journal editors are faced with the challenge of getting capable reviewers who are ready to volunteer their time, with a result being delays in reviewing, reviewer exhaustion, and worse, compromised quality. Meanwhile, AI technologies are accelerating their ability to review scientific manuscripts for methodology, statistical fitting, plagiarism screenings,...
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3 Answers 2 Votes
What is the most important research material in protein bioinformatics? 1. Protein sequence 2. Protein structure 3. Protein-related Software 4. A high-speed computer
A protein's sequence contains its intrinsic properties as a code. Nobel laureate scientist, C. B. Anfinsen proved it through experiments. Unlike sequence, since structures are man-made and obtained under different laboratory conditions, they may contain human error. Further, unlike nucleic acid, to date, the protein-folding code is unknown. So, in my opinion the study of protein sequence is primary. It is better if one can include structure study with it. But little can be said about this...
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32 Answers 23 Votes
To what extent can AI be used in scientific writing?
Routine aspects of inspection and considerations include, but not limited to: Obtaining the research question and hypothesis, choosing statistical analytic approaches and methods, data Interpretation, English editing, content Generation, drawing conclusions, etc. These are just several aspects, however, the potential hazards include the risk of bias, uniform tone in writing, lack of creativity, etc. Although with supervised use all these aspects can be partially controlled, to what extend do...
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0 Answers 0 Votes
In developing bioresorbable metallic implants for bone applications, what do you think are the biggest challenges?
Presently, a lot of research is going on based on magnesium, zinc, and iron for being used as temporary implants for orthopedic applications. Despite its advantages, widespread adoption in clinical settings still presents numerous challenges.
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46 Answers 27 Votes
What are the most promising areas of research for the next 5 years?
1. Artificial intelligence and machine learning 2. Genetics and personalized medicine 3. Climate change and environmental science 4. Neuroscience and brain-computer interfaces
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4 Answers 5 Votes
Which is the best technique for the quantitative analysis of microplastics/nanoplastics?
Accurate quantitative analysis of microplastics/nanoplastics is a challenging task for researchers across the globe. To develop reliable analytical methods is crucial for assessing this emerging pollutant effectively.
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1 Answer 0 Votes
How can advancements in bioinformatics tools and multi-omics integration (genomics, transcriptomics, and proteomics) improve the early diagnosis of cancer in 2024?
How can bioinformatics tools optimize the integration of multi-omics data to identify highly specific and sensitive biomarkers for early cancer diagnosis? · What role does artificial intelligence play in analyzing complex biological datasets, and how can its predictions be validated for clinical use? · What challenges exist in the standardization of bioinformatics pipelines for regulatory approval and widespread clinical adoption? · How can researchers address issues such as data...
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Answer Accepted 90 Answers 52 Votes
What is the time limit for reviewing an article?
For the review of each article, there is a value to be given to the reviewer.
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Answer Accepted 1 Answer 1 Vote
As an editor for peer-reviewed journal, what would you consider appropriate in making a decision to accept a peer-reviewer's report?
When evaluating a peer-reviewed study on surface water resources used for a commercial water operation, it is expected that the reviewer will thoroughly assess the methodology, including water sampling procedures and data analysis. In addition, the reviewer should identify potential oversights and suggest necessary improvements or alternative methods. However, when an expert reviewer raises concerns, and the authors respond with contrary submissions supported by well-detailed references, how...
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