Pings
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3 Answers 0 Votes
In austere/conflict settings, when does a complex surgery become ethically unjustifiable due to a lack of postoperative resources for managing complications?
As surgeons, we are trained to operate to solve a clinical problem. However, in severely resource-limited or conflict environments, this principle is constantly tested. Consider a scenario: A surgeon has the technical skill to perform a complex procedure (e.g., a pancreaticoduodenectomy for a tumor, or a complex limb salvage after trauma). However, the hospital lacks a reliable ICU, has inconsistent access to blood products, cannot provide parenteral nutrition, and has limited options for...
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4 Answers 0 Votes
What threshold of urinary cadmium (Cd-U) is currently considered indicative of early renal tubular dysfunction in exposed adult populations?
I am conducting a study on chronic environmental cadmium exposure and its nephrotoxic effects, particularly focusing on early biomarkers of renal tubular damage. Several sources suggest 2 µg/g creatinine as a reference point, but variability exists depending on population, sex, and co-exposure. Could experts clarify which threshold (e.g. 1 µg/g, 2 µg/g, or 5 µg/g creatinine) is most reliable or currently used in risk assessments and clinical practice?
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6 Answers 0 Votes
No threshold approach in the risk assessment of genotoxic carcinogen. Is it still well supported by current knowledge of carcinogenesis?
No threshold approach is routinely applied in the risk assessment of genotoxic carcinogens. How this approach is supported by data? Isn´ t it somewhat obsolete?
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8 Answers 3 Votes
A serious threat to human population in near future is the energy crises. What could be the plausible solution?
Global energy crisis is putting serious threats to the world's population recently. Mitigation and adoptation strategies are helping to overcome this issue but to a lesser extent. What should be the way forward?
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23 Answers 2 Votes
What are the benefits of strong collaborations between academia and the industry?
It is said that lack of relevant relationships between the industry and academia impede industrial innovations, as a strong bond between both can revolutionise global economy. What is your take on this and what benefits can such relationship between both parties bring?
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Answer Accepted 8 Answers 9 Votes
Why do qualified researchers from low- and middle-income countries often miss out on international roles despite meeting all requirements and how can they improve their chances?
I’m interested in understanding the hidden barriers and practical steps they can take to strengthen their applications
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5 Answers 2 Votes
Role of humanized immune system mice in to study the infectious and systemic inflammatory disease.
Whether the humanized immune system (HIS) mice help developing therapeutic interventions against infectious and inflammatory diseases? Whether HIS mice may revolutionize the translational biomedical research
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1 Answer 0 Votes
How can advances in electrochemical CO₂ conversion improve scalability of carbon-to-fuel technologies while minimizing energy demand and byproduct formation?
As a specialist in CO₂ reduction, my work focuses on advancing pathways that move beyond capture and storage toward scalable, value-added solutions. Current approaches including mineralization, electrochemical conversion, and bio-catalytic processes show potential but face challenges of efficiency, energy demand, and long-term stability. A critical next step is identifying how chemical, mineral, or catalytic enhancements can accelerate these processes while maintaining sustainability and...
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Answer Accepted 19 Answers 5 Votes
Impact of Food Regulation on Chronic Disease
To what extent do you believe strict governmental regulation of food safety and marketing could reduce the incidence of chronic diseases in the population? - Up to 30% - Around 50% - Up to 70% - Minimal effect - It depends on cultural factors
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8 Answers 4 Votes
How do you justify (or would you justify) a new research study to ensure it doesn’t unnecessarily duplicate previous work or repeat past methodological mistakes?
I’m currently working on a PhD thesis focused on Evidence-Based Research (EBR), particularly on how researchers use (or fail to use) prior evidence (similar studies), to justify and design new research. I’d love to hear real-world experiences, whether from preparing research proposals or evaluating them. Do you use any structured or unstructured method to be aware of all relevant prior research? How do you support your judgments (e.g., demonstrating that no prior studies exist, or that...
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