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0 Answers 0 Votes
What is friccohesity chemistry and how is the friccohesity be measured?
The genesis of this question could be derived from a continuity between the cohesive forces expressed as surface tension and the adhesive or frictional forces operated as viscosity. The monolayer adhesion noted as monodispersion resonate the molecular energies generating the friccohesity resonating energy transfer (FRET) equipartitioning the interfacial energy to nanoformulate the quality products. The following books could be...
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Answer Accepted 7 Answers 2 Votes
Human, in particular, are vulnerable to virus infection. what is the benefit of this devastation and why? 1. lowering human-population. 2. evolution. 3. increasing viral population. 4. none.
Viruses cause various diseases especially in humans. In many cases many people die at the same time. No specific cure for this problem is currently known in medicine. This virus has two forms one, in inside and other, in outside of the host. Host-infection of viruses is highly specific at the molecular level. So, I think it has a biological benefit.
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3 Answers 0 Votes
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18 Answers 8 Votes
Is Oxidative Stress sufficient by itself as an indicator and compelling basis for a carcinogenic concern?
Oxidative Stress as a Precursor and Mechanism for Carcinogenicity IARC and others (Smith et al) have identified 10 key characteristics which may be used/considered in the evaluation of carcinogenicity, one of which is oxidative stress. How strong or compelling, if at all, would the data need to be for considering OS as a putative and defensible MOA for carcinogenicity, or would there need to be other tangential/correlative data (e.g., tumors) available. In other words, is OS sufficient by...
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12 Answers 3 Votes
Any herbal medicines used for hepatitis, possible mechanism of action, and if possible attached pictures of plants with citations
Any herbal medicines used for hepatitis, possible mechanism of action, and if possible attached pictures of plants with citations
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10 Answers 8 Votes
Why Covid cases are still increasing and not under the control?
Why Covid cases are still increasing and not under the control?
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7 Answers 0 Votes
How long does it take for a glycoprotein to be synthesised de novo, processed in the ER/Golgi apparatus and transported to the cell membrane?
The trafficking time probably depends on the specific protein, but a ballpark average time is what I'm after. Please include references or examples.
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Answer Accepted 1 Answer 1 Vote
Can Levodopa and Renin-angiotensin system alter the intercellular tight junction (TJ) proteins in the epithelial cells in colorectal adenocarcinoma cell line (in vitro)?
Colorectal adenocarcinoma cell line (Caco-2) express tight junctions from 17-21 days. Levodopa is the precursor of dopamine, a well-known neurotransmitter, owever it also porduce effect in the gut. The renin-angiotensin system is responsible for maintaining homeostais and regulate blood pressure and volume.
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1 Answer 0 Votes
What is the most potential drug candidate in computer-aided drug design?
The drug-discovery process is highly costly and time-consuming. Thus, computer-aided drug design has become a very popular field and got applications. As the drug is used in human subjects, the protocol/technique/procedure to drug-design should be highly generalized and comprehensive. Generally high docking-scored drugs are considered best drug-candidates. I guess we should also check whether the best-scored drug satisfies any of the ADMET parameters. I think the optimum scored drug is...
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4 Answers 3 Votes
How do you call an outcome if you have multiple endpoints to investigate it?
Hello, When you want to investigate exacerbations (outcome of interest) in asthma, you can measure: 1) the incidence rate in the last year (i.e. mean numbers of exacerbations in the last year in your total population); 2) the frequency of patients reporting one exacerbation in the last year; 3) the time-to-1st-exacerbation within the last year. So you have 3 different endpoints to explore the same outcome. Could you please help me in finding the technical term to define this property of the...
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