What are recent machanism of actions, minmum duration of years of heat exposure and minimum temperature required for various heat induced skin cancers, also opnion for Kangri Cancer to be answered

There are various heat induced cancers in world.Duration of exposure,minmum temperature required for inducing pre-malignant changes, sites of cancers are uner review.
Mechanism of action is important in these cases

Anyone having more knowledge of mechanism of action for Kangri Cancer or other heat induced cancers

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